Nanocarrier Drug Delivery Systems: A Revolutionary Approach In Targeted And Controlled Therapies

Abstract

Nano nano (NDDS) drug delivery systems uses particles between 10 to 1000 nm and is utilized to increase targeted and controlled release of medications. They permit transportation across biological barriers, such as the blood brain barrier, as they enhance bioavailability and thus drug solubility. This resultant high precision and limited exposure of the system, offers NDDS as a major breakthrough superior to conventional dosage forms. As regards the evolution of nanocarrier, the systems that have been studied most are liposomes, polymers and dendrimers that all use active and passive targeting mechanisms, as well as responsiveness to exogenous signals. Existing uses are in cancer, infectious, and neurological diseases, cardiovascular treatment and also in improving adherence by patients. However, setbacks remain when it comes to biocompatibility, immune recognition, scalable production, as well as regulatory issues, and repeated innovation quests. Preclinical and clinical validation with fine details indicates that NDDS can be a transformational platform that can revamp drug administration and therapeutic effects in a wide range of areas in medicine.