Navigating The Metabolic Pathways Of Meftal: Implications For Women's Well-Being

Authors

  • Divneet Kaur
  • Prachi Sharma
  • Rekha Rana

Keywords:

Meftal, Nonsteroidal Anti-Inflammatory Drug (NSAID), Metabolism, Adverse Reactions, Pharmacokinetics and Pharmacodynamics

Abstract

Introduction: This comprehensive analysis explores the background and significance of Meftal, a nonsteroidal anti-inflammatory drug (NSAID), amidst recent safety concerns related to DRESS syndrome. The objective is to provide an in-depth understanding of Meftal's mechanisms of action, metabolism, and associated risks to guide future research and clinical practice. Methods: The analysis incorporates a review of existing literature, drug safety alerts, and clinical data pertaining to Meftal. Emphasis is placed on elucidating its metabolism in healthy individuals, covering aspects such as absorption, distribution, liver biotransformation, and excretion pathways. Additionally, the analysis delves into pharmacokinetic and pharmacodynamic variability and explores metabolic alterations induced by Meftal in various disease states. Results: The analysis reveals the diverse spectrum of side effects and complications associated with Meftal, including skin rashes, metabolic acidosis, thrombotic thrombocytopenic purpura, and acute pancreatitis. It highlights the importance of monitoring and reporting adverse reactions in response to recent safety alerts issued by regulatory authorities. Moreover, the variability in Meftal's metabolism and its impact on efficacy and safety profiles are discussed, along with hidden risks such as cardiovascular effects, gastrointestinal complications, and nephrotoxicity. Conclusion:  This analysis provides a comprehensive understanding of Meftal's metabolism and associated risks, emphasizing the need for vigilant monitoring and reporting of adverse reactions. Future research directions, emerging trends, and potential therapeutic innovations are discussed to address existing research gaps and challenges in Meftal's clinical use. Ultimately, the aim is to inform clinical practice and guide the development of safer and more effective therapeutic strategies involving Meftal.

Author Biographies

  • Divneet Kaur

    School of Pharmacy, Desh Bhagat University, Mandi Gobindgarh, Punjab

  • Prachi Sharma

    School of Pharmacy, Desh Bhagat University, Mandi Gobindgarh, Punjab

  • Rekha Rana

    School of Pharmacy, Desh Bhagat University, Mandi Gobindgarh, Punjab

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Published

2025-07-01

Issue

Section

Articles

How to Cite

Navigating The Metabolic Pathways Of Meftal: Implications For Women’s Well-Being. (2025). The Quintessential, 45-55. https://thequintessential.co.in/index.php/files/article/view/160

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